I was born in 1964, received my medical degree from the Faculty of Medicine at the University of Belgrade in 1989. In 1994, I became a neurologist. Over the course of my career, I took part in many additional courses, most notably: - a 6 month course in electroencephalography at the Institute of Neurology(1991) - a pediatric and neonatal EEG course at the University Hospital for pediatrics (1996) - ultrasonography of main head and neck blood vessels and transcranial doppler training (2000) In regards to my work experience, I have worked from 1989 until 2002 at the General Hospital in Pozarevac. In 2002, I moved to the Hospital for cerebrovascular diseases “Sveti Sava” in Belgrade, and have been there since. Today, my work mainly revolves around the latest treatments of blood vessel thrombosis, thrombolysis and thrombectomy. Since 2008, I have published numerous research papers both domestically and internationally. In 2014 I obtained the title of a primarius, the highest domestic distinction for a clinical physician.

treatments of blood vessel thrombosis, thrombolysis and thrombectomy

Marina Zueva, Professor of Pathophysiology, graduated from the Lomonosov Moscow State University (Physiology of Higher Nervous Activity), received her Ph.D. and Biol. Sci. D. from Moscow Helmholtz Research Institute of Eye Diseases. Currently, she is the Head of the Division of Clinical Physiology of Vision at the Moscow Helmholtz Research Institute of Eye Diseases. She has published over fifteen peer-reviewed full-length papers in English (over 100 in Russian) and presented near 70 topics at international conferences. Research Topics: Clinical physiology and electrophysiology of vision, neurophysiology; age-related and neurodegenerative disorders of the visual system and the brain, neurocognitive technologies of the restoration, maintenance and improvement of the brain activity and cognitive functions.

neurophysiology and neurodegenerative disorders of the visual system and the brain

Dr. M.Rajajeyakumar, MBBS, MD (Physiology), MSc Yoga, CCEBDM (PHFI), (PhD), has completed his MD Physiology,(2006-2009) at (JIPMER- An Institution of National Importance under the Ministry of Health & Family Welfare, Govt. of India). He worked as research assistant (2009-2012) in Advanced Centre for Yoga Therapy, Education & Research Lab, and JIPMER. He has published more than 50 research papers and serving as an expert reviewer (>28) and editorial board member (>52) in many national and international journals. Invited for honorable guest Speaker in Fitness-2015, Philadelphia, USA, and Speaker and chairperson for the international conference 9 th Indo global summit on cancer therapy -2015, India. He was selected as Speaker and chairperson for 12th,13th& 14 th AsiaPacificMedicalEducationConference-3rd, 4 th & 5 th International Conference on Faculty Development in the Health Professions, Yong Loo Lin School of Medicine, NUS, Singapore 2015,16 & 17. He presented his scientific paper in World Diabetes Congress Dec-2015, IDF,Vancouver, Canada. He appointed as Advisory Council members of Pure Action, Yoga is Medicine, Austin, TX 78703, USA.

Dr. M.Rajajeyakumar has been actively involved in research. His special research experience is in Yoga, autonomic, cognitive, cardio-respiratory, neurophysiology and medical education. He had trained with basic Physiological procedures including human and animal experimental physiology; pulmonary function test (PFT), autonomic function test (AFT), HRV (heart rate variability), EMG (electromyography), & NCS (nerve conduction study) related research.

Dr. DeFeo is noted as one of the leading experts of the DSM-5 in the State of California. She has conducted over 50 state, national, and international trainings on the topic. Dr. DeFeo was the highlighted presenter at the 18th Annual Inter-national Violence, Abuse, and Trauma Conference (IVAT) in San Diego in September, 2013, the 18th Annual IVAT Conference in Honolulu, Hawaii in March, 2014, and the Illinois American Association for Marriage and Family Therapy Annual Conference in Naperville, Illinois to conduct a full 7 hour workshop to educate Clinical Psychologists, Social Workers, Marriage and Family Therapists, Psychiatrists, and Medical Doctors/Professionals on the DSM-5 and ICD-10 diagnostic systems. Dr. DeFeo’s DSM-5 and ICD-10 training is also an approved accredited workshop with the Association for Advanced Training in the Behavioral Sciences (AATBS) to train social workers, psychologists, psychiatrists, medical physicians, and marriage and family therapists in the United States. Additionally, Dr. DeFeo is working with the Mexican Board of Professionals to institute the DSM-5 into the Mexican Higher Education Institutions, and has presented this topic at the First Annual Psychological Society Conference in Buenos Aires, Argentina in October, 2014 and various locations in Mexico (Tijuana, Ensenada, and Mexicali). Dr. DeFeo presently is a California licensed psychologist, distinguished professor of psychology, and Interim Associate Chair for the Department of Marriage and Family Therapy at the Chicago School of Professional Psychology in Irvine, California where she has been working since 2010. Dr. DeFeo also is a senior reviewer and editor for the Journal of Psychiatry, OMICS, and the Journal of Hispanic Higher Education.

Dr. George Perry is currently the dean of the College of Sciences and professor of biology at the University of Texas at San Antonio. After graduation in Zoology from University of California, Santa Barbara, he headed to Scripps Institution of Oceanography and also studied at Hopkins Marine Station of Stanford University and the Marine Biological Laboratory of Woods Hole and obtained his PhD in Marine Biology in 1979. Dr. Perry joined the faculty of Case Western Reserve University in 1995, where he currently holds an adjunct appointment. He is a Fellow of the American Association for the Advancement of Sciences, Microscopy Society of America, Royal Society of Medicine, Royal Society of Chemistry, Society of Biology and the Linnean Society and past-president of the American Association of Neuropathologists. He has been elected member of the Spanish Royal Academy of Sciences, Mexican Academy of Sciences and Academy of Sciences Lisbon; Iberoamerican Molecular Biology Organization, Dana Alliance for Brain Initiatives and won the Distinguished Professional Mentor Award from the Society for the Advancement of Chicanos and Native Americans in Science, Senior Investigator Award from the International College of Geriatric psychoneuropharmacology, Senior Fulbright Fellow and the National Honor Plaque of Panama for exceptional contributions to Neuroscience. Dr. Perry is on Board of the National Organization of Portuguese Americans and serves as Director of Education and Research.

Guy H Fontaine has made 15 original contributions at the inception of pacemakers since early 60s. He has serendipitously identified Arrhythmogenic Right Ventricular Dysplasia in the late 70s. He has published more than 900 scientific papers including 201 book chapters. He was the reviewer of 17 journals in Clinical and Basic Science. He served during 5 years as a Member of the Editorial Board of Circulation. He has been invited to give 11 master lectures of 90 minutes each during three weeks in the top universities of China (2014).

Dr. Wang is Director of Neuroapoptosis Drug Discovery Laboratory, Department of Neurosurgery, Brigham and Women’s Hospital/Harvard Medical School. Dr. Wang received her PhD from Hebrew University of Jerusalem. She did her postdoctoral training at University of Michigan and Harvard Medical School. Dr. Wang has published about 70 peer-reviewed articles and has served as the Guest Editor, Handling Editor, and Editorial Board Member for a number of peer-reviewed journals, as well as the scientist reviewer for institutes or foundations including NIH, DOD, BSF, and others, and invited reviewer for 34 peer-reviewed journals.

Currently I am working as Research Scientist in the Department of Neurology at University of Iowa, Iowa, USA. I did my B.Sc. (Chemistry) in 2003, M.Sc. (Organic Chemistry) in 2005 from Aligarh Muslim University and Ph.D. (Toxicology) in 2009 from the department of Toxicology, Hamdard University, Delhi, India. After completion of my Ph.D. program, I have joined the Department of Internal medicine as postdoctoral Research Associate. Here I focused my research on understanding the role of plasma glycoprotein von Willebrand factor (VWF) and VWF-cleaving protease ADAMTS13 in animal model of stroke. After that I joined the department of Neurology as an Associate Scientist. Here my research investigates the molecular mechanisms that regulate inflammation in the central nervous system that are critical to our understanding of a broad spectrum of neurodegenerative diseases, including Parkinson’s disease, stroke, Alzheimer’s disease, multiple sclerosis and traumatic brain injury. I am the member of several international societies and enlisted in the Editorial board of the journal.I have published almost 40 peer reviewed original research publications and almost 50 abstracts in National and International Neuroscience-related meeting and conferences.

Professor WK Tang was appointed to professor in the Department of Psychiatry, the Chinese University of Hong Kong in 2011. Professor Tang completed his medical training at the Chinese University of Hong Kong. He joined the Chinese University of Hong Kong as an academic staff since 1999. His main research area is Neuropsychiatry in Stroke. Professor Tang has published over 100 papers in renowned journals, and has also contributed to the peer review of 40 journals. He has secured over 20 major competitive research grants. He has served the editorial boards of five scientific journals. He was also a recipient of the Young Researcher Award in 2007, awarded by the Chinese University of Hong Kong.

Kurt A Jellinger, born 1931 in Vienna, is Professor of Neurology and Neuropathology at the Medical University of Vienna (Vienna, Austria), was director of the Department of Neurology, Lainz Hospital in Vienna and since 2002, director of the Institute of Clinical Neurobiology (Vienna, Austria). He has been the recipient of numerous international grants and awards, is a member of numerous national and international scientific societies, editor of many international journals of neurology, neuroscience and neuropathology. His publication records exceeds 1,000 in perr-reviewed journals, 170 contributions in scientific book, inclduding several as editor, as well as 1.300 lectures at international meetings. For the last 50 years, his research included many fields of clinical neuropathology, neurochemistry and descriptive neurobiology.

Dr. Federoff will oversee and guide the development of UC Irvine Health. In addition to leading the School of Medicine, he will provide strategic direction for the clinical programs of UC Irvine Medical Center and all affiliated patient care centers and will ensure the alignment of the clinical enterprise and the physicians’ practice plan with the university’s academic and research missions. He will also provide guidance on the development and integration of UCI’s health-related academic programs in nursing science, public health and pharmaceutical sciences.

pharmaceutical sciences, nursing science

David has worked in community based mental health services in the UK for over thirty years developing services for people with complex care needs and enduring mental health problems in a career spanning the voluntary sector, local authority services, and the NHS.. From 2009 - 2011 he was the Dementia Implementation Lead for Commissioning Support for London, working with commissioners across London to improve dementia services. He is an independent writer and researcher on dementia support and services for Black and minority ethnic communities, working with a number of projects and initiatives.

Dementia, Mental Health

Partner at a personal injury law firm specializing in T.B.I. The National Trial Lawyers “Top 100 Trial Lawyers”. BS Magna Cum Laude 1990 and Juris Doctorate 1993. Vice-Chairman of B.O.D. Mothers Against Drunk Driving National. & B.O.D. Brain Injury Alliance. 20x year keynote at National Brain Injury Conferences. All honorariums donated to charities. Authored Spring Break: A True Story of Hope and Determination regarding a brain injured college student who received long-term inpatient, outpatient care and rehabilitation. Awarded: US Senate Official Proclamation, US Congressional Citation, U.S. House of Representatives Special Congressional Recognition, 20+ awards for legal and charitable accomplishments.

Traumatic Brain Injury

Mootaz Salman is a pharmacist and researcher PhD student at the Biomolecular Sciences Research Centre (BMRC) at Sheffield Hallam University, working with Prof. Nicola Woodroofe and Dr. Matthew Conner’s research group and a member of the multi-institute Aquaporin research collaboration. His research interest focus on the identification of new drug targets for brain oedema and epilepsy through his work on the special water channels called “Aquaporins”. Mootaz graduated with Outstanding Distinction in his MSc winning the Sheffield Hallam University prize for the most scientific contribution and ranked 1st in year. His PhD research requires the skilled use of numerous techniques ranging from standard biochemical and molecular biology to cutting edge micro-array and laser confocal microscopy. Mootaz is an international ambassador at Sheffield Hallam University, ambassador for British Society of Experimental Biology (SEB); and STEM ambassador since 2014. He has given four invited oral presentations and talks at major international conferences in Canada, Netherlands, Romania and Japan along with three talks at a national level. He is also an active member in a number of scientific societies nationally and internationally including USA, Canada and Japan. He has been selected to be an abstract reviewer at two major international conferences; Brain 2015 in Canada and also for the upcoming Brain 2017 in Berlin, along with being an abstract reviewer and a member of poster judgement panel during the North of England Postgraduate Conference (NEPG) which is the UK's largest annual postgraduate conference for medical biosciences. Mootaz has successfully participated in organising a number of national and international high profile conferences and also he has been selected to chair scientific sessions at two national events.

Molecular Pharmacology, Neurochemistry, Astrocytes and Cerebral Aquaporins

Dr. Federoff will oversee and guide the development of UC Irvine Health. In addition to leading the School of Medicine, he will provide strategic direction for the clinical programs of UC Irvine Medical Center and all affiliated patient care centers and will ensure the alignment of the clinical enterprise and the physicians’ practice plan with the university’s academic and research missions. He will also provide guidance on the development and integration of UCI’s health-related academic programs in nursing science, public health and pharmaceutical sciences.

pharmaceutical sciences, nursing science

Jane Verity is the Founder of Spark of Life and CEO of Dementia Care Australia. Jane is a world leader and pioneer in the social and emotional care of people with dementia. Originally from Denmark and now living in Melbourne, Australia, Jane is an Occupational and Family Therapist and a Master Practitioner in NLP. She has earned the highest international accreditation as a professional speaker and is known for her life changing presentations. Jane has authored 2 internationally published books and contributed to others. She is also a regular contributor to journals and an international key note presenter.

social and emotional care of people with dementia

Post TBI patients comprehensive care for headaches and cognitive rehab, neck pain and back pain. Neuro cognitive evaluation, treatment and rehabilitation for early recovery. Dr Kumar provides forced oxygen therapy for acute and sub acute concussion/ mild traumatic brain injury and treatment of other neurological disorder routinely in his office. Comprehensive Traumatic Brain Injury Center 1. Screening for our football/basketball players/contact sports for concussion head injury 2. Immediate forced oxygen therapy for Mild TBI patients. 3. Treatment and control of physical symptoms of the MTBI 4. 1 hour EEG and MRI brain DTI test for MTBI evaluations 5. Neurocognitive testing and neuro behavioral testing with in first week of the MTBI to plan neurocognitive therapy or neuro-rehabilitation 6. Visio-spatial/Speech/ occupational/ Computer based neurocognitive therapy 7. Early recovery from MTBI with providing other support systems. Urgent Headaches Clinic 1. We treat Walk-in headache patients 2. Iv infusion and Oxygen therapy for headaches 3. Nerve blocks and Botox therapy for headaches Neurology Clinic 1. Non Narcotics treatment of headaches, neck pain, upper & lower back pain 2. Peripheral neuropathy or limb pain 3. Seizure disorder 4. Dementia 5. Post stroke therapy or other neurological disorder Gene Based Medication Therapy 1. All Our patients are enrolled in gene based medication therapy. Genetics based medication therapy to ensure the medication efficacy and decrease side effect for headaches and seizures disorders. 2. We have joined hand with John Hopkins in research study to provide gene based medication therapy. Neurology Research Center 1. Active research site for multi-center research trial 2. Active research site for our own services. 3. Publishing research to contribute and create knowledge

Neurology, Cognitive science

Molecular biologist interesting in iron metabolism and 5'UTR based RNA therapeutics for helping individuals suffering from neurodegenerative diseases.

Molecular biology, neurology

David has worked in community based mental health services in the UK for over thirty years developing services for people with complex care needs and enduring mental health problems in a career spanning the voluntary sector, local authority services, and the NHS.. From 2009 - 2011 he was the Dementia Implementation Lead for Commissioning Support for London, working with commissioners across London to improve dementia services. He is an independent writer and researcher on dementia support and services for Black and minority ethnic communities, working with a number of projects and initiatives.

Dementia, Mental Health

Partner at a personal injury law firm specializing in T.B.I. The National Trial Lawyers “Top 100 Trial Lawyers”. BS Magna Cum Laude 1990 and Juris Doctorate 1993. Vice-Chairman of B.O.D. Mothers Against Drunk Driving National. & B.O.D. Brain Injury Alliance. 20x year keynote at National Brain Injury Conferences. All honorariums donated to charities. Authored Spring Break: A True Story of Hope and Determination regarding a brain injured college student who received long-term inpatient, outpatient care and rehabilitation. Awarded: US Senate Official Proclamation, US Congressional Citation, U.S. House of Representatives Special Congressional Recognition, 20+ awards for legal and charitable accomplishments.

Traumatic Brain Injury

Deputy National Stroke Guide line in collaboration with Royal College Physician of UK • Prepared Stroke clinical Pathway currently used at Royal Hospital • Teacher and final MD and OMSB examiner • Speaker Sohar Second Medicine Symposium, 24/3/2013, • Speaker&Moderator 1st Kuwait North American Conference, April 2013 • OMSB Examiner 2013,2014 and up to date • Organizer &Speaker of Stroke Care Teaching Modules 1st/mar/2014 Sohar Hospital • Organizer &speaker: MS updates Sohar Hospital 2013, 2014 & Nov 20th / 2014 • Speaker & Organizer at 9GCC Neurology conference 6-8 /Nov/2014 • Contributors of the National diabetic guide line (prepared the diabetic neuropathy Module) • Chair Person & Speaker at the First Omani German Stroke Conference 21-22/Feb./2015 • Moderator 2nd Kuwait North American Conference, December 2014 • Chair Person Scientific Committee ,Organizer & Speaker 1st OMA 4-5/11/2015

Neurology, Medicine

Professor and head of department in Grant Medical College & Sir JJ Group of hospitals 1991-2002. Professor Emeritus - Grant Medical College & Sir JJ Group of Hospital September 2005 till date. National coordinator for World Federation of Neurology Education Continuum-CME programme since 2005. Member of the WHO International Advisory Group for the Revision of ICD 10, Diseases of the Nervous System in the area of Infections of the Nervous System - January 2010 Member - World Federation of Neurology Education Committee since 2010 till date. Chair - World Federation of Neurology Teaching Course Committee 2014.

Neurology

BUSINESS OWNER - MASTER KARATE INSTRUCTOR - SALES PROFESSIONAL - TEACHER Truly a Man of the World with a proven professional track record in business of increased sales, drastic volume growth and tremendous interpersonal, written and oral communication skills. Offers a strong record of performance maintaining relationships & exceeding sales plans. Sole Business Owner at Oasis Senior Advisors, a franchise in the Lehigh Valley of Pa. Proud Peace Corp Volunteer in Morocco, North Africa. Lived/ Trained Japanese Karate in Japan for SEVENTEEN YEARS. Currently teaching Japanese Karate Classes

Senior care, dementia care

Canadian dancer and fitness instructor, Jill Simpson, spent nearly a decade as caregiver to her father who had Lewy body dementia, a form most often associated with Parkinson’s disease. A decade later, returning to the world of dance, Jill was hired by the Alzheimer’s Society of Ontario to become as one of six Mind’s in Motion® physical activity leads in its ground breaking pilot program investigating the effects of exercise on early to mid-dementia. The more I learned, the more I kept thinking about my dad, and how this information might have helped him had I just known more about the most recent dementia research. The research led to the realization that as I dancer, as well as a fitness instructor, I was in a unique position to combine four of the most powerful activities for staving off cognitive decline: music, dance, aerobic activity, and cognitive challenge into a single program not only for those with early to mid dementia, but for a general population who simply want to keep their brains tuned up. The Body, Mind, and Movement Program™ for Brain Fitness is a unique combination of music and specific types of movement designed to stimulate blood flow to the brain, increase connectivity and communication between right and left hemispheres, and flood the brain with natural exercise-induced hormones that elevate mood and stimulate cognition. Jill has also recently trained and partnered with Dancing with Parkinson’s (DWP) Sarah Robichaud in Toronto to bring the DWP program to the Kitchener/Waterloo area. Although distinctly different, there is a great deal of overlap between the two programs as approximately 30% of those with Parkinson’s go on to develop a form of dementia, and finding alternate neural pathways is the goal of both programs.

Neurology

Born in 1968, he completed Medical Faculty University of Sarajevo 1997(MD degree). With IDU works since 1998 and since 1999 head of the ambulance to OST within the Mental Health Center Zenica. One of the founders of the Cantonal Institute for the disease of addiction Ze-Do Canton Zenica. In the period 2003-07 in the Cantonal Hospital Zenica and a University Clinical center in Sarajevo completed his residency in neurology and psychiatry. Medical Faculty in Sarajevo completed courses of good clinical practice and good experimental practices as well as postgraduate studies in clinical medicine(MSc degree). In the period 2013-15 ending sub-specialization in the field of addictology followed by planned training in the field of forensic psychiatry. Member of the expert group (2010-12) at the Department of Health of the Ministry of Civil Affairs, which has developed guidelines for the implementation of OST in B&H. UNODC internationally certified trainer in the field of substance abuse. The Cantonal Institute of addictions performed the following duties: a doctor in the clinic (2005-08), head of the hospital department (2008-12) a Head of all medical services and consultative addictologist. (2012-).Since 2013 employed as a forensic psychiatrist in Zenica and Busovaca prison and court expert in this field. Of the 2013 decision of the Minister of Health FB&H head of education in the field of addictology for employees Center for Mental Helath in FB&H.

Neurology

Advocate for the older population. Health Care Services for Older Adults through HOME VISITS. Older adults & family will be assisted in minimizing health risks through guidance and understanding of: -Personal responsibility for health status to maintain independence and control of health. -Health risk factors that occur with aging which can be modified to prevent complications and decrease risks. -Atypical responses to illnesses and treatment. -Education for compliance with medications and treatments as prescribed. -Improvement of nutrition, hydration, and activities for healthy lifestyle. -Approach to aging with the skill & enthusiasm required.

Aging, Nursing

Amy M. Clark, PhD is apart of the Dementia Care Ecosystem Project though UNMC and its partnership with the University of California - San Francisco. This project is funded by a 3-year, $10 million Healthcare Innovations Award from the Centers for Medicare & Medicaid. The impact of the Care Ecosystem will be studied, as it aims to support patients and their caregivers with decision-making, medications, caregiver support, online education, and, for a subset of patients, remote monitoring with smartphones, watches, and home sensors. Additionally Dr. Clark is a Visiting Professor with Nebraska Wesleyan University in the Social Work Department. Previously Amy served as the Dean of Health Professions at Nebraska Methodist College in Omaha, NE. In her role as Dean she oversaw 19 undergraduate, graduate and certificate on-ground and online programs in the health professions division. She was responsible for ensuring that the Allied Health Programs offered at NMC maintain their accreditation standards, enhance the student educational experience on campus and online through leadership of faculty and staff, strategic planning, curricular quality and efficiency, program integrity, and student satisfaction. Dr. Clark is a two-time Excellence in Teaching Award winner and has presented at local, state, and national conferences on a variety of topics related to teaching and research within the online and traditional on-ground educational settings.

neurology, dementia care

Born in Jammu-Tawi, India. After receiving Bachelor’s degree in Pharmaceutical Technology from the Birla Institute of Technology, Pilani, India, Rameshwar K. Sharma in 1960 entered the University of Connecticut for graduate work in Medicinal Chemistry and received his Ph.D. in 1963. Subsequently, after several Post-doctoral positions, including at the Worcester Foundation for Experimental Biology, Shrewsbury, Massachusetts, he joined the University of Tennessee Medical Center at Memphis in 1970 where he rose to the rank of Full Tenured Professor of Biochemistry and Physiology. During this period through NIH Special Fellowship he spent two-years Sabbatical as a Visiting Professor at the McArdle Laboratory University of Wisconsin, Madison, in Dr. Henry Pitot’s lab, and subsequently additional two-years Sabbatical at the NIH, Bethesda in Dr. Michael Cashel’s lab. After Full Professorship at the Case Western University and Founder and Head of the Unit of Regulatory Biology at the Cleveland Clinic Foundation, Cleveland Ohio, he joined the University of Medicine and Dentistry at New Jersey as the Professor and Head of The Unit of Regulatory and Molecular Biology. Since July 2006 he is at the Salus University as a Distinguished Professor of Biochemistry and Molecular Biology. In a period spanning four decades, his research team has dedicated itself to the advancement of the field of membrane guanylate cyclase in the vertebrate systems. A few of its core findings that have impacted this and the field of cellular signal transduction follow. (1) With the discovery of the first membrane guanylate cyclase, ANF-RGC that was also the hormone receptor of ANF, the membrane guanylate cyclase surface receptor family was established. (2) It had a unique signal transduction mechanism. Instead of GTP in G-Protein signaling, it was regulated by ATP through its ARM module (ARM). The complete dissection of the module, followed through the concept-based analysis, localized a WTAPELL motif that controlled the entire signal transduction process, it was, then, predicted that this motif is the one that controls the ANF-RGC-dependent blood pressure in vasculature. This has now been proven true through the construction of the mouse genetic model. The mice lacking this motif are hypertensive. (3) The discovery and molecular characterization of the photoreceptor ROS-GC is a land mark event in the phototransduction field. It filled in the gap on the identity of the source of cyclic GMP that serves as a second messenger of the LIGHT signal; and made it possible to explain the principles of phototransduction in molecular and physiological terms. It also impacted the core membrane guanylate cyclase field by branching it into two: a transducer of both the hormone receptor and the intracellularly-generated Ca2+ signals. (4) ROS-GC field took additional direction when it was demonstrated that, besides phototransduction, it is biochemically linked with the transduction mechanisms of the inner segments of the retina, olfactory cilia and the olfactory bulb neurons. (5) The demonstration that ROS-GC is a Ca2+-bimodal switch, generated a new revolutionary concept where theoretically ROS-GC could be modulated through two different modes of Ca2+ signaling: via Ca2+-sensor GCAPS and S100B, the latter stimulating it and the mode found exclusively in cones and absent in rods. (6) Recently, an additional model of the photoreceptor ROS-GC1 has been disclosed. ROS-GC1 is responsive to the bicarbonate signal; it is not the pH effect, rather it binds to a specific motif of the ROS-GC and transduces the signal in generation of cyclic GMP. Preliminary findings suggest that this novel transduction system is present in a small number of mouse cones, and, importantly, is absent in the rods. This opens up a new area of sensory transduction mechanism, where it is meant to communicate with the external atmospheric carbon dioxide. The carbon dioxide is sensed through carbonic anhydrase, whose subtype has been detected in some cones, it converts CO2 to the bicarbonate, which, then, becomes the second messenger of CO2 and a signaling agent of ROS-GC1. Threaded through this past history and step-by-step gain in the field, This investigator feels fortunate that his group has made these important contributions in generating the field of membrane guanylate cyclase, establishing that cyclic GMP is an ubiquitous intracellular second messenger in prokaryotes and eukaryotes and that it plays a critical role in the control of physiological processes of cardiac vasculature, smooth muscle relaxation, blood volume, cellular growth, sensory transduction, neural plasticity, learning and memory. It is also gratifying to know that during this course he has been able to train and guide more than 35 doctoral and post-doctoral students, author 184 peer-reviewed research articles, including the editorship of three books, Special Editorship of two journals of Molecular and Cellular Biochemistry and the e-book editor of the Frontiers Molecular Neuroscience Research Topic, all focused on the field of membrane guanylate cyclases. At present I am on the editorial board of four international journals: Associate editor of the Frontiers in Molecular Neuroscience, Journal of Molecular and Cellular Biochemistry, Journal of Signal Transduction, Journal of Membrane Science & Technology. I am also the founding father and the President of the Guanylate Cyclase Innovative Biotechnology

Neuropharmacology

Kurt A Jellinger, born 1931 in Vienna, is Professor of Neurology and Neuropathology at the Medical University of Vienna (Vienna, Austria), was director of the Department of Neurology, Lainz Hospital in Vienna and since 2002, director of the Institute of Clinical Neurobiology (Vienna, Austria). He has been the recipient of numerous international grants and awards, is a member of numerous national and international scientific societies, editor of many international journals of neurology, neuroscience and neuropathology. His publication records exceeds 1,000 in perr-reviewed journals, 170 contributions in scientific book, inclduding several as editor, as well as 1.300 lectures at international meetings. For the last 50 years, his research included many fields of clinical neuropathology, neurochemistry and descriptive neurobiology.

His current research is focused on the neuropathology, molecular pathology and pathogenesis of movement disorders, neurodegenerative dementias, vascular cognitive disorders, late-life dementia and problems of cell death in CNS aging.

Anne cared for her husband at home until his younger onset Frontal Temporal Dementia required Residential Care. She still actively shares in his care. Prior to this she held National Senior Executive positions in large organisations, founded her own Management Consulting business and has been involved as a Director on many Statutory Boards & Government Advisory Committees. Her career commenced as a Registered Nurse in Operating Theatre Management, before moving into strategic corporate HR/Occupational Health & Safety Management. She is an active member of Alzheimer’s Australia (Vic) ‘Consumer Advisory Committee’, the Victorian Department of Health & Human Services – ‘ Public Sector Residential Aged Care - Reference Group’ & was appointed as Victorian representative to the ‘National Consumer Advisory Committee’ of Alzheimer’s Australia 2014 . She is a regular guest speaker, promoting greater understanding about the different forms & stages of Dementia including the Behavioural, Psychological & Communication changes that arise with the development & diagnosis of Dementia. She has held a Consumer Directed Home Care Package & has been involved in many Alzheimer' Australia (Vic) projects including ‘Driving & Dementia’, 'Intimacy & Dementia' & ‘Dementia Friendly Communities’.

Psychology, Behavioral Sciences

Panteleimon Giannakopoulos has completed his MD at age of 23 years from the University of Athens and is board certified psychiatrist and psychotherapist from 1999. He completed his postgraduate training in London and Paris before taking the chair of old age psychiatry in Geneva. He has also a full training in cognitive neurosciences focusing on dementing conditions. He was the chairman of the Department of Psychiatry in Geneva from 2005 to 2015 before being appointed as medical director of the Forensic Psychiatry for the Geneva county. He has published more than 220 peer-reviewed articles (h index: 42), and has been serving as an editorial board member and reviwer of repute.

Identification of markers of cognitive decline in mild cognitive impairment, late-onset depression and bipolar disorders, Cognitive impact of vascular lesions in brain aging, Alzheimer’s disease (AD), Use of recombinant clusterin to prevent ischemic damage in organotypic cultures and after middle cerebral artery occlusion

Marco Tulio Medina, born in the city of Tegucigalpa , MDC capital of the Republic of Honduras , on September 19, 1959, is a researcher in the fields of neurology and epilepsy, currently serves as Dean of the Faculty of Medical Sciences , UNAH . Founded in 1998, the Graduate Neurology at the UNAH with the support of the World Federation of Neurology (WFN), becoming a pilot program to developing countries, thus promoting education and neurological research in Honduras.

epilepsy genetic, neuro‐epidemiology and vascular endothelium

Doctor. Faculty of Medical Sciences, National University of Cuyo. Neurology residency. Private Community Hospital of Mar del Plata. Head of Residence, Residence of Neurology. Private Community Hospital of Mar del Plata. Doctor in medicine. Faculty of Medical Sciences, National University of Cuyo. Specialist in University Teaching. Faculty of Arts, National University of Cuyo.

Neurology, Neuropharmacology, Medical Sciences

As a post doctoral student, She is Interested in 1) Factors that enhance brain neuroplasticity, slowing the progression of neurodegenerative diseases; 2) Early surrogate biomarkers; 3) Development of new therapeutic strategies for patients with dementia; 4) Support therapies for relatives of patients with dementia and the effects of exercise and vascular risk factors in cognitive decline and dementia in the elderly.

dementia, vascular neurology, cognitive science

Dr. Soraya L. Valles completed her PhD in Alcohol action mechanisms with Consuelo Guerri her Director of Thesis (1996) from Instituto Investigationes Citologicas, in Valencia, Spain. Postdoctoral position in Sheffield, UK with Dr. Eva Qwarnstrom and Steve Dower. During 3.5 years, working in inflammation and IL-1R1 (from 1997 to 2000). Postdoctoral position in Spain, with Dr. Consuelo Guerri, working in alcohol and inflammation (from 2000 to 2004). Lecturer position in school of medicine, University of Valencia. Department of Physiology (from 2004 to 2008). Senior lecturer in the same University, (from 2008 to 2009). She is presently working as an Assistant professor in department of Physiology, school of medicine, University of Valencia.

Biochemistry, Genetics and Molecular Biology Neuroscience Medicine

Toshimitsu Musha right after he retired from Tokyo Institute of Technology, aiming at developing new EEG analysis technologies for non-invasively estimating signal processing in the brain. The first target was prevention of the sudden death coming from the mental overwork of workaholic people. Eventually he has reached a new technique of reading a dynamic change of our mind. This technique expresses the emotional state as an emotion vector in the 4-D rectangular coordinate system spanned by four orthogonal sates: stress, joy, depression, and relaxation. This technique has been named ESAM for Emotion Spectrum Analysis Method. This is now widely used in industries for measuring the degree of satisfaction of users of their new products and for objective evaluation of our living environments.

Alzheimer's disease, Dementia

Toru Itakura has completed his MD at the age of 24 years from Wakayama Medical University and postdoctoral studies from Wakayama Medical University School of Medicine. He is President of Wakayama Medical University and Professor of Department of Neurological Surgery. He has published more than 200 papers in reputed journals.

Dementia

Eef Hogervorst did her Ph.D. at Maastricht University in age related cognitive decline and treatment at the Department of Psychiatry and Neuropsychology in 1998. She was subsequently employed at the University of Oxford (Oxford Project to Investigate Memory and Ageing, OPTIMA) as a neuropsychologist and epidemiologist and was awarded several grants and prizes for her research into early diagnoses and risk factors for dementia and cognitive decline. Eef did similar research as a Research Associate Professor at the Donald W. Reynolds Department of Geriatrics (ranked 8th nationally) of the University of Arkansas Medical Sciences and at the University of Cambridge (Department of Psychiatry) as Senior Research Associate, before taking on a Chair in Psychology at Loughborough University which is consistently ranked among the top Universities in the U.K. Eef has set-up collaborations with several large multi-centre observational and treatment studies for age related cognitive decline and dementia (EPIC NORFOLK and MRC CFAS in the U.K. and the H ABC, WHIMS and KEEPS studies in the U.S.A and a large cohort in Indonesia). She studies cross cultural clinical diagnostic accuracy of different types of dementias and has developed and validated a computerized expert system and cognitive test battery for this purpose with Dr Bandelow.  Eef is an elected member of the MRC College of Experts for Neuroscience and Mental Health, a member of the European Scientific Referee panel for the European Research Area in Ageing and is often asked to review research proposals (Alzheimer Association, NWO, SPARC etc) and papers in her field (Neurology, JNNP, Arch Neurol, etc). She was invited as a keynote speaker at several conferences (e.g. ICAD). At Oxford Eef was Somerville Junior Research fellow and Blasschko fellow at Linacre College. Eef is an elected young Fellow at the Royal Society of Medicine in London, Editor (Section Head) of the International Faculty 1000, on the editorial board of JAD and has over 100 international  peer reviewed publications.

Alzheimer's disease

Professor Martine Simard

Neuropsychology, Alzheimer's disease, Working Memory, Parkinson's Disease, Assessments, Geriatric depression, Neuropsychiatry, Psychopharmacology, Dementia with Lewy bodies, Cognitive stimulation

Professor Amos D. Korczyn is the Sieratzki Professor of Neurology at Tel-Aviv University. Professor Korczyn graduated from the Hebrew University – Hadassah Medical School in Jerusalem in 1966 (MD), where he also received an MSc degree in pharmacology (cum laude) in 1966. He trained in neurology at Beilinson Hospital and at the National Hospital for Nervous Diseases in Queen Square, London. He was the Chairman of the Department of Neurology at the Tel-Aviv Medical Center since 1981 until 2002. Professor Korczyn has a particular interest in dementia. He has authored or co-authored over 600 articles in peer-reviewed journals, as well as chapters in books, etc. Professor Korczyn is or has been an Editorial Board member of 15 international journals, and organized several neurological conferences, mainly in the field of dementia, Parkinson’s disease and other degenerative brain disorders.

Perry received his bachelors of arts degree in zoology with high honors from University of California, Santa Barbara. After graduation, he headed to Scripps Institution of Oceanography and obtained his Ph.D. in marine biology under David Epel in 1979. He then received a postdoctoral fellowship in the Department of Cell Biology in the laboratories of Dr. Bill Brinkley and Joseph Bryan at Baylor College of Medicine where he laid the foundation for his observations of abnormalities in cell structures. In 1982, Perry joined the faculty of Case Western Reserve University, where he currently holds an adjunct appointment. He is distinguished as one of the top Alzheimer’s disease researchers with over 800 publications, one of the top 100 most-cited scientists in neuroscience and behavior and one of the top 25 scientists in free radical research. Perry has been cited over 23,000 times and is recognized as an ISI highly cited researcher. Perry is editor for numerous journals and is editor-in-chief for the Journal of Alzheimer's Disease. He is a fellow of the American Association for the Advancement of Sciences and past-president of the American Association of Neuropathologists, as well as a member of the Dana Alliance for Brain Initiatives. Perry is recognized internationally for his work. He is a Foreign Correspondent Member of the Spanish Royal Academy of Sciences and a Foreign Member of the Mexican National Academy of Sciences, and recent recipient of the National Plaque of Honor from the Republic of Panama Ministry of Science and Technology.

Dr. Eric Tangalos is Professor of Medicine at the Mayo Clinic in Rochester, Minnesota. He was Chair of Primary Care Internal Medicine from 1997 to 2006. Dr. Tangalos received his undergraduate training from the University of Michigan, is a graduate of the Loyola University Stritch School of Medicine in Chicago, and was a resident and fellow in Internal Medicine at Mayo. He served eight years on the National Board of the Alzheimer’s Association and was a member of their Executive Committee. He continues as Co-Director of Education for the Mayo Clinic Alzheimer’s Disease Research Center and has been continuously funded by the National Institutes of Health since 1987. He is part of the original group to publish on Mild Cognitive Impairment.

Piotr Lewczuk, leads the Laboratory for Clinical Neurochemistry and Neurochemical Dementia Diagnostics at the Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen. This lab is one of the mostly internationally-recognized, European leading centers for neurochemical diagnosis of dementia. The Laboratory is one of the five world-wide reference centers, together with the laboratories in Göteborg (S), Amsterdam (NL), Ghent (B), and Philadelphia (USA), in the \"Alzheimer\'s Association\"-supported project on CSF biomarkers international quality control. He is a member of the Steering Committee of this project. For more than ten years he has been working on diagnostic and research aspects of the CSF, including a large panel of neurologic and psychiatric disorders with a particular scope on neurodegenerating conditions, like Alzheimer\'s disease. In 2004, he obtained the Certificate of Expertise from the German Society of Clinical Neurochemistry, to become one of seventy certified clinical neurochemists in Germany, and currently he is a member of the Extended Board of the German Society of Clinical Neurochemistry.

Dr. Buchanan is a board certified specialist in both neurological surgery and psychiatry. He is trained in and performs all aspects of neurosurgery including those for disorders of the brain, spine, and peripheral nerves. Dr. Buchanan also has subspecialty training and surgical expertise in epilepsy, deep brain stimulation, Parkinson\\\'s disease, essential tremor, Tourette syndrome, and dystonia, as well as pain syndromes and psychiatric disorders such as major depression and OCD. Dr. Buchanan is dedicated to helping patients recover both physically and psychologically. Dr. Buchanan completed his residencies at the University of California San Diego (UCSD) School of Medicine in the Department of Psychiatry and the Department of Surgery/Neurosurgery. His fellowships include Yale University School of Medicine, Department of Neurosurgery, in Epilepsy Surgery and Functional Neurosurgery; UCSD Department of Psychiatry and the National Institute of Health (NIH) Psychobiology and Psychopharmacology as well as The Salk Institute for Biological Studies, Post-Doctoral Fellow with the Lab of Genetics. Dr. Buchanan is an Associate Professor in the Department of Psychology and The Institute for Neuroscience at The University of Texas at Austin and The University of Texas Southwestern Medical School. He has an Image Guided Transcranial Laboratory at UT where he studies Brain Function and is exploring treatments for epilepsy, psychiatric disease, and movement disorders. Dr. Buchanan is a Board Certified Diplomate of both the American Board of Neurological Surgery and the American Board of Psychiatry and Neurology.

Fangyu Peng, M.D., Ph.D., is a physician-scientist who practices clinical nuclear medicine, with research interests in PET translational imaging and cancer therapy. Dr. Peng is studying copper metabolism as a target for metabolic imaging and therapy of cancers, including prostate cancer and hepatocellular carcinoma. Dr. Peng is also conducting translational research in molecular imaging of inherited and acquired copper metabolism disorders in Wilson\\\'s disease, Alzheimer\\\'s disease, and traumatic brain injury.

Eef Hogervorst did her Ph.D. at Maastricht University in age related cognitive decline and treatment at the Department of Psychiatry and Neuropsychology in 1998. She was subsequently employed at the University of Oxford (Oxford Project to Investigate Memory and Ageing, OPTIMA) as a neuropsychologist and epidemiologist and was awarded several grants and prizes for her research into early diagnoses and risk factors for dementia and cognitive decline. Eef did similar research as a Research Associate Professor at the Donald W. Reynolds Department of Geriatrics (ranked 8th nationally) of the University of Arkansas Medical Sciences and at the University of Cambridge (Department of Psychiatry) as Senior Research Associate, before taking on a Chair in Psychology at Loughborough University which is consistently ranked among the top Universities in the U.K. Eef has set-up collaborations with several large multi-centre observational and treatment studies for age related cognitive decline and dementia (EPIC NORFOLK and MRC CFAS in the U.K. and the H ABC, WHIMS and KEEPS studies in the U.S.A and a large cohort in Indonesia). She studies cross cultural clinical diagnostic accuracy of different types of dementias and has developed and validated a computerized expert system and cognitive test battery for this purpose with Dr Bandelow.  Eef is an elected member of the MRC College of Experts for Neuroscience and Mental Health, a member of the European Scientific Referee panel for the European Research Area in Ageing and is often asked to review research proposals (Alzheimer Association, NWO, SPARC etc) and papers in her field (Neurology, JNNP, Arch Neurol, etc). She was invited as a keynote speaker at several conferences (e.g. ICAD). At Oxford Eef was Somerville Junior Research fellow and Blasschko fellow at Linacre College. Eef is an elected young Fellow at the Royal Society of Medicine in London, Editor (Section Head) of the International Faculty 1000, on the editorial board of JAD and has over 100 international  peer reviewed publications.

Eef research interests are early diagnoses and modifiable risk and protective factors (e.g. hormones, exercise and nutrition) for dementia and age related cognitive decline; development and validation of cognitive tests and computerized diagnostic systems.

Lydia Gimenez Llort graduated in biology continued with the doctoral and postdoctoral three years at the Karolinska Institute in Sweden. She is now a researcher in neuroscience (aging and neurodegenerative diseases such as Alzheimer's) and professor in psychiatry at the Autonomous University of Barcelona.

Alzheimer's Disease, Animal Models, Neurodegenerative Diseases, Cognition Disorders Cognitive Neuroscience, Behavioral Neuroscience Neuropharmacology, Behavioral Testing Behavioral Analysis, Rat Handling, Behavioral, Pharmacology, Maze Learning, Microdialysis, Neurologic Kindling, Neuropsychopharmacology, Behavioral Neuroendocrinology, Brain